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While youre not likely to run into MPTP (unless youre taking synthetic street drugs), it is chemically similar to a commonly used herbicide called paraquat.[ref] Subsequently, a number of studies have shown that higher paraquat exposure increases the risk of Parkinsons disease.[ref] Monoamine Oxidase increases ROS: When monoamine oxidase breaks down a monoamine (neurotransmitters, tyramine, etc.), the reaction produces hydrogen peroxide and possibly ammonia, which are reactive oxygen species (ROS)

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Thats because NAD coenzymes impact pathways in the body that modify aging, according to a 2021 UK study that included human and animal data

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(2012) support that E2 regulates the expression of Bcl-2, an anti-apoptotic protein, and survivin, which inhibits caspase activation, by the suppression of different miRNAs, including miR-16, miR-143 and miR-203

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