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LTB4 is a lipid mediator derived from arachidonic acid by the sequential action of 5-lipoxygenase (5-LOX), 5-lipoxygenase-activating protein (FLAP) and LTA4 hydrolase (LTA4H) to stimulate leucocyte functions such as cytokines, chemokinesis, lysosomal enzyme release, superoxide anion production, adhesion to endothelial cells, generation of ROS and so on

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NMR-based metabolic profiling was used to identify the metabolic properties of four cell lines: control MCF7 cells, which are tamoxifen-sensitive, and three tamoxifen-resistant MCF7 cell lines, by performing univariate and multivariate data analyses

(b) The oxidation of the PrSH yields a thiyl radical (RS ), which reacts with the deprotonated form of glutathione (GS ), forming a mixed disulfide radical (RSSG )

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