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Similarly, tirzepatide is more effective at supporting weight loss than semaglutide but seems to have a poorer safety profile

See a healthcare provider immediately if you experience: An inability to eat Persistent or severe nausea that impacts your daily life Signs of dehydration (extreme thirst, dizziness, dry mouth, peeing less often) If your nausea is severe, consult with your prescribing physician or your GI team

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In contrast, more than 80% of those starting SGLT2 or insulin added another medication

Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1

In addition, patients with HF can have their cardiac function and prognosis assessed using 6MWT, NT-proBNP, and QoL [51]