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Adicionalmente, los mltiples efectos pleiotrpicos de SEMA sobre la funcin metablica, heptica y renal pueden contribuir de forma indirecta a la proteccin cardiovascular25

Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

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For patients with atherosclerotic cardiovascular disease and diabetes, the combination of modest lipid improvements alongside other cardioprotective mechanisms may contribute to overall risk reduction

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Even a modest weight reduction can provide relief for conditions like sleep apnea, sometimes eliminating the need for bulky breathing devices used to treat it