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Preclinical studies have explored GHK-Cu effects in cardiovascular applications, where the peptide demonstrates capacity to reduce atherosclerotic plaque formation in hyperlipidemic mice through anti-inflammatory effects and improved endothelial function

Among the identified metabolites, only Ac-LKKTE exhibited in vitro wound healing activity, indicating that previous functional effects attributed to TB-500 may be due to this specific metabolite (Rahaman et al

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