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10.1016/j.imr.2019.11.002 45

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Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

Although TR/GR-null livers generate some of their cysteine through the serine transsulfuration pathway, we here show that most cysteine in TR/GR-null livers comes from a pathway in which pyridoxal-phosphate-dependent cleavage of a carbonsulfur bond in cystine generates cysteine persulfide, which decomposes nonenzymatically into cysteine

H.de RoodeJ

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