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It works as both a copper carrier and a GLP-1 (glucagon-like peptide-1) is a hormone the gut releases after you eat

And, if theyre ultimately approved, it will also serve as another example of Kennedy getting his way over the objections of the researchers who work for him.

"Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice." Biochemical Pharmacology

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A 26-week diabetes study measured human activity at 1 mg, but its endpoint was blood sugar rather than long-term weight. A short outpatient cohort measured about 4.7% weight loss over four weeks at 2.5 mg. Below 1 mg, estimates rely on pharmacokinetics and mechanism

Here's how the components break down for CPT 96372