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doi: 10.1017/S1092852916000651

TBK1 then phosphorylates and activates both the IRF3 pathway and the NF-B pathway, triggering the transcription of proinflammatory cytokines, antiviral chemokines, interferon-stimulated genes (ISGs), and type I IFNs

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10.1007/s00018-008-7526-3 Cell Mol

The dose depends on their age, weight, and why they need B12

The sample size was determined based on the following rationale: for system consistency validation, ninety-six parallel samples ( n = 96) were analyzed to comprehensively cover all detection channels of a single 96-well plate, a number that far exceeds conventional requirements for microbiological method validation and aims to provide highly stable mean and relative standard deviation (RSD) values