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SGLT2i use is associated with an increased risk of DKA and UTI, but confers several favourable outcomes, notably preservation of renal function, reduced risk of developing heart failure and CKD, and of hospitalisation, despite a higher prevalence of heart failure, hypertension, IHD and CKD at baseline

Adjusting injection dosage for side effects Side effects are the primary reason people deviate from the standard titration schedule

10.1210/jc.2003-030049

FDAs approval of the Wegovy pill is based on the results gathered from the OASIS 4 Phase III clinical trial, a 64-week medical study including 307 adults with obesity or overweight with one or more weight-related comorbidities, without diabetes

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