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Muller U, Moll G
Ceramides can help to strengthen the skin's barrier layer, which can help to prevent the penetration of melanin into the skin
Ophthalmology 125 , 815821 (2018)
Stress, overconsumption of alcohol, food intolerance, microbial imbalance and poor nutrition can affect the integrity of the epithelial barrier
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It competitively binds p53, displacing endogenous FOXO4 in senescent cells (Baar et al., 2017) 24-72 hours: Freed p53 translocates to mitochondria in senescent cells, triggering the intrinsic apoptotic cascade
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