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However, the studys results are limited by the short-term outcome measurement, which leaves long-term effects and mechanisms unknown

Human pharmacokinetic data remain limited and most IGF-1 magnitude claims come from animal studies or small uncontrolled series

The phase 3 REDEFINE program, published in The New England Journal of Medicine and presented at the American Diabetes Associations Scientific Sessions in June 2025, put the combination to the test

Results vary depending on your starting levels and health goals

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Willner, P., Scheel-Krger, J