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So how can the clinical physician optimize the immunosuppressive therapy after identifying a patient with a suspected unfavorable outcome because the patient is a fast metabolizer

Reduction of ischemic brain injury by topical application of insulin-like growth factor-I after transient middle cerebral artery occlusion in rats

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The table below summarises the classic dosage tiers studied during dose-ranging

In addition, Ebselen has high bioavailability, good tolerability and efficacy in acute ischemic stroke, bipolar disease, and neurological disorders (Forman and Zhang 2021)