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Neither formulation is universally better

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In studies on the human hepatocellular carcinoma cell line HepG2 as well as the undifferentiated and pre-differentiated fibroblastic mouse cell line 3T3-L1 under non-inflammatory and inflammatory conditions, it was found that the hypoglycemic activity of LF may be related to the improvement of insulin resistance by regulating the expression of glycoprotein genes and thus exerting the anti-inflammatory mechanism of its activity (44, 45)

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The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene

The NLRP3 inflammasome serves as a double-edged sword in carcinogenesis, mediating protective immune responses while driving pathological inflammation when dysregulated (He et al., 2016)