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Our study showed that the MBC of amikacin for the MRAB isolates tested was about four fold higher compared to its MIC (4 g/ml) (Table 3 and Supplementary Figure S2)

MOTS-c was found to upregulate key genes in the TGF-/Smad pathway (such as TGF-1, TGF-2, and Smad7) and increase the expression of bone formation markers like alkaline phosphatase (ALP), osteocalcin, and Runx2 in bone cells