Q 2: Is dual-action therapy more effective than GLP-1 alone
Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice
If constipation arises post-therapy, support with fluids, fiber, gentle activity, and perhaps a brief trial of over-the-counter fiber supplements during clinician consultation
Who May Benefit and Critical Provider-Guided Considerations Liposomal glutathione may be considered for individuals with documented oxidative stress, compromised intestinal absorption, or conditions requiring antioxidant support
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(ii) have the ability to chelate metal ions such as iron and copper, inhibiting peroxidation reactions of fatty acids and phospholipids in cell membranes [86]