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Butyrate is known to stimulate GLP-1 secretion from intestinal L-cells through activation of specific receptors
Sandberg, L
Maruthur et al
The key thing to understand about GLP-1 medications like these is that the tablet form requires strict empty-stomach protocols because food destroys absorption almost completely
This effect of GLP-1(2836) was independent of the known GLP-1R and was mediated by a mechanism involving mitochondrial MTP and intracellular sAC in caSMCs and caECs but not CMs
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