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Muscle, tendon, and ligament repair: Accelerated healing of tendon and ligament injuries, improved muscle regeneration, and enhanced biomechanical strength, with higher local levels of growth factors such as VEGF, bFGF, and EGF in healing tissues

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This synergy is the scientific rationale for the combination

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Similarly, because phentermine is a sympathomimetic and anorexic agent (i.e., psychostimulant) it should not be used in combination with other sympathomimetics or psychostimulants for weight loss, including OTC preparations, and herbal products that may contain ephedra alkaloids or Ma huang