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It was originally isolated on the basis of inhibitory effects on acid secretion in canine isolated gastric pouches, but this effect could not be reproduced under physiological circumstances in humans (21), and gradually the meaning of the acronym (GIP): Gastric Inhibitory Peptide, changed to glucose-dependent insulinotropic polypeptide

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Chou OHI, Lu L, Chung CT, Chan JSK, Chan RNC, Hiu ALY, Dee EC, Ng K, Pui HHH, Lee S