10.1038/s43856-023-00369-8 56 MuskietM
GLP-1 Analogs When choosing a GLP-1 receptor agonist, options include long-acting vs short-acting agents, the need for reconstitution, patient preference, health insurance coverage & cost to the patient
Interestingly, the medications that may be the most effective at achieving the desired outcome can be the ones that are more likely to cause adverse effects
GLP-1s support weight loss by: Delaying gastric emptying, which helps you feel fuller for longer after meals Regulating blood sugar, which can support steady energy and fewer cravings Reducing appetite and food noise by acting on hunger-regulating areas of the brain While Ozempic, Wegovy, Foundayo, and Zepbound all fall under the GLP-1 umbrella, Zepbound is unique in that it also targets another hormone called GIP (glucose-dependent insulinotropic polypeptide)
If you cannot keep fluids down and have not had a bowel movement in several days, seek emergency care
36 Dedicated Heart Failure Trials The STEP-HFpEF, STEP-HFpEF DM and SUMMIT trials represent key advances in the evaluation of GLP-1RAs in the treatment of HF