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doi: 10.1016/j.jpain.2016.11.004 94 Hylands-WhiteNDuarteRVRaphaelJH

COMBINING GLP-1 AND ESTROGEN LEADS TO SYNERGISTIC EFFECT ON WEIGHT LOSS, GLYCEMIC CONTROL, AND FOOD REWARD Hypothalamic GLP-1R expression increases during late proestrus, when estrogen levels are high GLP-1 secretion from pancreas or intestinal cells is increased in direct action of estrogen in these cells