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The high acid load can irritate the gastric mucosa, trigger severe acid reflux, and cause osmotic diarrhea by drawing excess water into the bowel

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Researchers study cyclic adenosine monophosphate (cAMP) production, protein kinase A (PKA) activation, -arrestin recruitment, receptor trafficking, phosphorylation cascades, and transcriptional regulation

Instead, the scLCDV1-VILP bound to domain L1 makes a sparse contact with domain FnIII-1 in the vicinity of residue His539

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Some risk factors cannot be changed, such as age and genetics