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There are several medical options available to decrease melanin in skin and manage hyperpigmentation

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Neurochem Res 22:727733 Li X, Wallin C, Weber SG, Sandberg M (1999) Net efflux of cysteine, glutathione and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glutamyl transpeptidase

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Despite this relatively short half-life in circulation, the downstream metabolic effects persist for significantly longer due to the sustained activation of lipolytic enzymes and metabolic pathways initiated by the peptide