are tirzepatide and mounjaro the same vs Mounjaro: What's Difference? Switch to Tirzepatide in T2D

Kidney Function: Semaglutide can cause dehydration, which may lead to kidney problems, especially in patients with pre-existing kidney conditions

Efectos gastrointestinales y deshidratacin: El uso de agonistas del receptor de GLP-1 se puede asociar con reacciones adversas gastrointestinales que pueden causar deshidratacin, lo que en raros casos puede producir a su vez un deterioro de la funcin renal (ver la seccin de Reacciones secundarias y adversas)

At week 52, mean percentage change in body weight compared to baseline was -10.7%, -13.3%, and -15.6% in the 5 mg, 10 mg, and 15 mg tirzepatide arms compared to -0.8% in the placebo arm

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You have not achieved your weight loss goals through diet and physical activity alone

[2] Consider adding desmopressin (off-label)