Kynurenine is predominantly metabolized to the N -methyl-d-aspartate (NMDA) receptor agonist quinolinic acid (QUIN) in the inflammatory state, contributing to the accumulation of glutamate in the extracellular space, leading to changes in network connectivity associated with depression, fatigue and cognitive impairment
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Am J Clin Nutr 1989
ENDOMETRIOSIS: nutritionists Point of View Nutrition and Endometriosis Although the pathophysiology of endometriosis is multifactorial, involving hormonal, immunological, genetic, and environmental contributors, growing attention has been given to the role of nutrition as both a modifiable risk factor and a potential adjunctive therapeutic approach [10]