As a result, it was later approved specifically for obesity and overweight management under the name Zepbound
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Using a linear trimming estimator in the trim and fill model, one study was attributed to the left side of the funnel plot
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The rate of having another stroke was similar between patients who did and did not receive either medication, at approximately 6%
While its safety profile was consistently favorable, the largest Phase IIb trial failed to show statistical significance for weight loss, and commercial development was halted in 2007.[2] Despite this, interest in AOD-9604 has continued in the compounding pharmacy and integrative medicine space, particularly given its safety data, its lack of IGF-1 stimulation, and emerging research around joint health