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The company also highlighted other savings from the new arrangement, including savings of as much as $3,600 per year compared to buying these medications directly from manufacturers or through consumer programs

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Similarly, in Kctd13 (a gene within 16p11.2 CNV) haploinsufficient and knockout mice, there was an increase in RhoA expression coupled with deficiencies in synaptic signalingan effect that was ameliorated with Rhosin treatment [137]