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The trial has two main arms: A structured lifestyle intervention program with intensive coaching and support A structured-lite version of the same core program with fewer touchpoints Both arms of the lifestyle trial will separately assess the impact of adding a metabolism-targeting drug such as a GLP-1 agonist to determine which combination offers the greatest cognitive protection

Understanding your genetic and metabolic context can support a more informed conversation with your provider about whether GLP-1 alone is appropriate for your situation, what dosing and formulation might be most suitable, and whether exercise integration is medically feasible or beneficial for your particular health profile