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10.1080/13697137.2018.1439915 Climacteric 42 DenleyM

Central melanocortin receptors mediate changes in food intake in the rhesus macaque*

Several studies employing single-cell RNA sequencing, mass cytometry, and fluorescence cytometry revealed phenotypic alterations in microglia across various models, although spatial information was limitedly obtained and the pathological mechanisms remained unclear at that time

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Kojima N, Williams JM, Takahashi T, Miyata N, Roman RJ

Clinical and observational literature reports measurable pigmentation changes alongside adverse effects, which helps frame safety-relevant endpoints in research design