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Serpinc1 acts as a tumor suppressor in hepatocellular carcinoma through inducing apoptosis and blocking macrophage polarization in an ubiquitin-proteasome manner

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But boy is this a field that moves rapidly

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As shown in Figure 5, the top ten compounds with the lowest binding energies were identified, with the strongest interaction observed between GSTM1 and Irinotecan (10.4 kcal/mol), indicating a stable binding affinity