Iddon JL, Morgan DJ, Loveday C, Sahakian BJ, Pickard JD
Participants received once-weekly subcutaneous retatrutide at 4 mg, 9 mg, or 12 mg, or placebo, for 80 weeks
But heres the kicker: the big benefits like beating diabetes or dodging heart attacks can take years to show up
GLP-1s Can Affect Fertility This may happen because the metabolic improvements caused by GLP-1s can help restore ovulation, especially for women with insulin resistance or polycystic ovary syndrome (PCOS), Gandhi says
Key Outcomes: Up to 24.2% total body weight reduction in high-dose groups
These FDA-approved medications for chronic weight management work by slowing gastric emptying and affecting appetite-regulating pathways, which can trigger gastrointestinal symptoms