Adding a GLP-1 drug could potentially heighten that risk in certain scenarios: the medication will make your pancreas secrete insulin when you do ingest carbs, and simultaneously it suppresses glucagon (the hormone that tells your liver to release glucose)
Xie X, Yang S, Deng S, Liu Y, Xu Z, He B
Subsequently, to further extend the effect of exenatide, Amylin and Eli Lilly developed exenatide injectable microspheres (Bydureon), which was approved in the United States in January 2012
84: GLP-1 Medications & Pregnancy: What We Know So Far: Ep
It doesnt replace them
SELECT CVOT trial investigated the cardiovascular safety of semaglutide 2.4 mg therapy once a week in a group of 17,605 overweight or obese adults over the age of 45 with no history of T2DM