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Yeast biotechnology: diversity and applications
The phase 2 clinical trial data showed that participants who began at higher starting doses experienced nearly double the rate of GI side effects compared to those who titrated gradually from lower amounts
For instance, SSRIs showed to have antimicrobial effects, mostly against Gram-positive microorganisms, acting as efflux pump inhibitors and having a synergistic activity when combined with some antibiotics
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Collectively, these findings suggest that in individuals with a genetic predisposition, the pathophysiology of migraine is characterized by repeated activation and sensitization of trigeminal nerves by meningeal inflammation, influenced by significant brain activity and resulting in structural and functional brain changes (36)
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