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We hypothesized that NAC administered during acute opioid withdrawal would decrease withdrawal behaviors, normalize [GLX], and increase [GSH] and [NAA] concentrations in the neonatal rat brain, thus providing neuroprotection from the oxidative stress of acute withdrawal

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Funding information iNOVA4HealthUID/Multi/04462/, a programme financially supported by Fundao para a Cincia e a Tecnologia-Ministrio da Educao e Cincia (FCT-MCTES) through national funds

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