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Hyperbilirubinemia is caused by either an increase in bilirubin production or a decrease in the hepatic uptake, conjugation, or excretion of bilirubin

For most individuals, despite the fact that carbidopa binds to Vitamin B6, vitamin levels remain normal because it is replenished readily in a balanced diet

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Loree JM, Dowers A, Tu D, Jonker DJ, Edelstein DL, Quinn H, Holtrup F, Price T, Zalcberg JR, Moore MJ, Karapetis CS, O'Callaghan CJ, Waring P, Kennecke HF, Hamilton SR, Kopetz S

Despite a recommended daily intake as low as 6 micrograms, B12 deficiency remains common, particularly among individuals following vegan or vegetarian diets

Phytate and plant-heavy diets Phytate in whole grains, legumes, nuts and seeds binds zinc and reduces absorption