Rather than targeting one receptor pathway with high specificity, retatrutide activates three distinct hormone receptors simultaneously: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon
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Those two receptor pathways GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are both involved in regulating appetite, blood sugar, and how the body processes food
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