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Nrf2 is a key regulator of redox homeostasis in the gastrointestinal tract, brain, kidney, liver, and skin, etc

Boston: 2004

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This pulsatile pattern is considered more physiologically appropriate than continuous GH elevation, and is preserved across multiple administration cycles

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Endogenous reactive oxygen species are produced by NAPQI linked to the thiol group of GSH, resulting in lipid peroxidation and cell death 60