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Author Contributions All authors contributed to the following during the development of this article: conception and design

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The American Heart Association, American College of Cardiology, and The Obesity Society endorse lifestyle therapy as first-line treatment for overweight and obesity

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As part of the AngioSafe 1 study, both an observational and interventional phase IV study of patients with T2D showed that GLP-1R agonists did not increase the risk for severe diabetic retinopathy (Gaborit et al., 2020)

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