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This study established a mechanistic link between integrin signaling and the production of 27-HC, an immunosuppressive oxysterol known to induce CD8 + T cell exhaustion within the TME

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FDAs Office of Inspections and Investigations (OII) Field Science Laboratories centrally manages the program, including interacting with DOD and coordinating laboratory work

This inconsistency may affect clinical outcomes and raise concerns about study results' reproducibility

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