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doi: 10.1074/jbc.RA120.015779 222 XiongLLiuYWangYZhaoHSongXFanWet al
Desmots F, Rissel M, Gilot D et al (2002) Pro-inflammatory cytokines tumor necrosis factor and interleukin-6 and survival factor epidermal growth factor positively regulate the murine GSTA4 enzyme in hepatocytes
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However, excessive free fatty acid oxidation or exposure to high quantities of toxins, such as alcohol or hepatotoxic medications, can result in aberrant ROS generation and the depletion of endogenous antioxidants
4 CUL5 regulates genetic material The regulation of genetic material synthesis and repair by CUL5 propels malignant tumor progression
Restoring NRF2 activity in iPSC-derived MSCs from HGPS patient fibroblasts increased their viability, indicating that NRF2 activation maybe useful in counteracting the premature exhaustion of adult stem pools normally seen in HGPS patients (Liu et al., 2011
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