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Indeed, the European multicenter study coordinated by Graham reports that, whereas basal hyperhomocysteinemia only shows an additive effect with hypercholesterolemia, it has a synergistic effect with both hypertension and smoking on the incidence of atherosclerotic vascular disease (Graham et al, 1997)

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Your doctor will consider factors like your current B12 levels, weight, age, and health goals

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It plays an important role in the metabolism of thyroid hormones and in the fight against oxidative stress (5)