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1 Introduction 1.1 Literature review methodology This review was conducted by searching PubMed, Scopus, and Google Scholar databases using the keywords Parkinsons disease, -synuclein, dopaminergic neurons, LRRK2, mitochondrial dysfunction, comorbidities, levodopa, and neuroinflammation. Studies published in English between 2000 and 2025 were included

at 4mg per administration, roughly 20

and severe GI adverse reactions were reported more frequently among patients who received semaglutide tablets (7 mg 0.6%, 14 mg 2%) than placebo (0.3%)

Usage Direction 1 teaspoon daily on an empty stomach, or as directed by a health care practitioner

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Macrophages, chronic inflammation, and insulin resistance