In a large observational study, 67,731 participants, who had no evidence of dementia, were non-diabetic, and aged 65 were followed from January 2004 to December 2009, to observe the onset of T2DM and compare the risk of the incidence of dementia associated with the use of anti-diabetic drugs and reported that metformin reduced the risk of developing dementia (256)
They mimic a natural gut hormone that signals fullness, slows stomach emptying, and helps the body use insulin more efficiently
S.BohnenG.GrobeN.RodriguesS
10.7 Clinical Bottom Line GLP-1 receptor agonists: Do not inherently cause universal nutrient depletion May increase intake-related vulnerability Require structured dietary strategy Benefit from risk-based monitoring Should be accompanied by protein prioritisation Weight loss and nutritional adequacy are not mutually exclusive
To provide better strategies for obesity, further research based on published studies is needed in the future
True digestive wellness and metabolic signaling are closely connected and when one is disrupted, the other often follows