A practical framework looks like this
GLP-1 receptor agonists resistant to DPP-4 degradation such as semaglutide, albiglutide, and dulaglutide have been developed, generating an extended half-life in circulation [15]
M.FriasJ
Exenatide has shown effectiveness in reducing motor defects in Parkinsons Disease by preserving dopaminergic neurons and enhancing neurotransmitter function, thus improving the overall outcome (29)
[9] [10] Your GP may wish to perform investigations to exclude other causes of tiredness, which might include: Blood tests : Full blood count (to check for anaemia), thyroid function tests, vitamin B12, folate and vitamin D levels, iron studies, renal and liver function, and HbA1c to assess overall glycaemic control
Same medication, but with slower escalation and clearer expectation-setting