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In brief, the peak area of the metabolite was normalized to the peak area of an isotopically labelled internal standard with similar elution time, both in samples from culture medium and external standard library dilutions

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doi: 10.1016/j.redox.2025.103543 76 RongYHuangLYiKChenHLiuSZhangWet al

It is FDA-approved for managing type 2 diabetes and can be prescribed off-label for weight loss

Whether long-term use leads to risks such as hypoglycemia and thyroid C-cell hyperplasia remains to be further evaluated

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