The breadth of the gene expression effects has been one of the more striking findings in the GHK-Cu literature, with some studies reporting effects on more than 4,000 genes at certain doses and exposure times
Human-equivalent dosing extrapolated from animal studies suggests 200 to 500 micrograms per day, administered subcutaneously for musculoskeletal or systemic targets and orally for gut-specific applications
This creates a net negative balance within adipocytes, resulting in decreased lipid droplet size and eventual adipocyte shrinkage
Dodatkowo pH witaminy C (~2,53,5) destabilizuje kompleks GHK-Cu, ktry dziaa optymalnie przy pH 5,57,0
During times of oxidative stress, the GST genes are upregulated
This could provide a beneficial effect on a host of inflammatory conditions, from arthritis to autoimmune diseases