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If the end-of-week dip bothers you, understanding the full semaglutide timeline helps calibrate expectations
Other stimuli that enhance calcitonin secretion include supraphysiologic concentrations of glucagon (48), 5HT1 receptor agonists (49) gastrin (and pentagastrin) (50), alcohol (51), and exercise (52) and glucagon-like peptide-1 (GLP-1) (53) A detailed discussion of each of these stimuli is beyond the limits of this chapter and the reader is referred to a review on this subject for more detail (54) The finding that glucagon-like peptide-1 (GLP-1) agonists, an effective therapy for type 2 diabetes mellitus, bind to GLP-1 receptors, stimulates CT release and cause MTCs in rodents has stimulated a broad discussion regarding their safety in humans (53)
Evidence Summary Consistent animal study results but no human data 2 Human 14 Animal 4 In Vitro 3 Reviews 23 Total This content is for educational purposes only and is not medical advice
Be alert for complications
De Sales-Milln et al., 2024
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