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Medications maintain therapeutic drug levels continuously, whereas food-stimulated GLP-1 secretion occurs in pulses after meals and is rapidly degraded

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Diabetologia 40 , 205211 (1997)

Third, even if the GLP-1 increase is real, the downstream effects depend on duration, receptor binding affinity, and overall systemic exposure

Patients interested in medical weight loss should speak with a licensed provider about currently available options, including tirzepatide and semaglutide when clinically appropriate

Heart health benefits: Weight loss and blood sugar control can significantly improve your overall cardiovascular outlook