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This is the single most cited reason community protocols pair the two

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Heres what they found: There was a higher risk of premature birth but only in women using GLP 1 to treat diabetes

A separate 2024 study of 290 adults with obesity given oral semaglutide for three months found that free T3 decreased, free T4 rose slightly, and TSH fell during treatment

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It may still occur occasionally, particularly after dietary indiscretions (high-fat meals, excessive alcohol, or unusually large portions), but the chronic, frequent pattern of the escalation phase is typically over