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This lack of lifestyle integration not only blunts weight loss (since diet/exercise contribute significantly), but also magnifies attrition patients who arent seeing lifestyle progress or feel unsupported are more likely to give up on the medication when challenges arise

In such cases, GLP-1 hormone can help contribute to glucose control by stimulating glucose-dependent insulin release, reducing glucagon secretion, slowing gastric emptying, and eventually enhancing satiety

For weight management, they are available only through specialist services for people meeting specific BMI and comorbidity criteria under NICE guidance

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