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This is further supported by the finding that SOD activity is increased during active disease and returns to normal in remission (157).Additionally, the presence of oxidative damage and the inhibition of catalase, an antioxidant enzyme, in CD patients immune cells further underscores oxidative stresss role in the disease (158)

This results in oxygen-deprived areas within the tumor tissue

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Menezo, Y., Elder, K., Clement, A

10.1111/ane.13551 54 LiS.GaurU.ChongC

Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli